GGUF vs AWQ: which quantization format should you use?

Compared on hardware support, runtime, quality and what the 110-model index actually ships.

At a glance

GGUF vs AWQ: which quantization format should you use?
GGUFAWQ
Runs onAny — CPU / NVIDIA / AMD / AppleNVIDIA GPU (CUDA 11.8+) or AMD via vLLM ROCm
Runtimellama.cpp · OllamavLLM · AutoAWQ · TGI
Best forLocal / edge deploymentHigh-throughput API server
Models in this index110 / 11053 / 110

GGUF

The most versatile format. CPU, GPU, Apple Silicon — runs everywhere. Supports hybrid inference splitting weights across RAM and VRAM.

Strengths

  • Any hardware
  • CPU+GPU hybrid
  • Huge ecosystem
  • Beginner-friendly

Trade-offs

  • Slower than GPU-native
  • Not ideal for high concurrency

AWQ

Activation-Aware Weight Quantization: 4-bit weights quantized with the activation statistics in hand, served mainly by vLLM on NVIDIA and on the AMD cards vLLM's ROCm build supports. On every model in this index that ships both, the AWQ INT4 file is smaller than GGUF Q4_K_M (median 18% smaller) and its published quality loss is higher (median 1.1 points more). AutoAWQ, the tool most AWQ builds were made with, is deprecated in favour of vLLM's llm-compressor; existing AWQ checkpoints still load.

Strengths

  • Smaller than GGUF Q4_K_M on every paired model here
  • Served by vLLM with continuous batching
  • Measured 218 tok/s (Llama 3.1 8B, RTX 4090, vLLM)

Trade-offs

  • Higher published loss than Q4_K_M on every paired model here
  • GPU only — no CPU or Apple path
  • AutoAWQ deprecated (llm-compressor replaces it)

Models that ship both

These 53 models publish weights in both formats, so the two rows describe the same model rather than two different ones — the only place this comparison is measurable rather than editorial.

Models that ship both
ModelGGUF LevelQuality lossAWQ LevelQuality loss
Llama 3.1 405B InstructQ4_K_M2.3%AWQ INT43.5%
Qwen3 235B-A22B InstructQ4_K_M2.2%AWQ INT43.2%
Llama 4 Scout 17B (16E)Q4_K_M2.4%AWQ INT43.2%
Qwen2.5 72B InstructQ5_K_M1.1%AWQ INT43.5%
Llama 3.1 70B InstructQ5_K_M1.2%AWQ INT43.9%
Llama 3.3 70B InstructQ5_K_M1%AWQ INT43.7%
DeepSeek-R1-Distill-Llama-70BQ4_K_M2.4%AWQ INT43.5%
Jamba 1.5 MiniQ4_K_M3.4%AWQ INT44.8%
Mixtral 8x7B InstructQ4_K_M2.8%AWQ INT43.8%
Seed-OSS 36B InstructQ5_K_M1.3%AWQ INT43.8%
Yi 1.5 34B ChatQ4_K_M2.8%AWQ INT44%
Qwen3 32B InstructQ4_K_M2.5%AWQ INT43.6%
Qwen2.5-Coder 32B InstructQ4_K_M2.5%AWQ INT43.5%
Qwen3 30B-A3B InstructQ5_K_M1.1%AWQ INT43.4%
Qwen3-Coder 30B-A3B InstructQ5_K_M1%AWQ INT43.2%
Qwen3-VL 30B-A3B InstructQ8_00.3%AWQ INT43.7%
Gemma 3 27B ITQ4_K_M2.8%AWQ INT43.8%
Gemma 2 27B InstructQ5_K_M1.3%AWQ INT44%
Mistral Small 24B InstructQ4_K_M2.9%AWQ INT43.8%
Devstral Small 1.1 24BQ6_K0.6%AWQ INT44%

Quality loss is perplexity increase against the unquantized weights — lower is better, and only comparable within one model.

Which to choose