GGUF vs AWQ: which quantization format should you use?

Compared on hardware support, runtime, quality and what the 79-model index actually ships.

At a glance

GGUF vs AWQ: which quantization format should you use?
GGUFAWQ
Runs onAny — CPU / NVIDIA / AMD / AppleNVIDIA GPU (CUDA 11.8+)
Runtimellama.cpp · OllamavLLM · AutoAWQ · TGI
Best forLocal / edge deploymentHigh-throughput API server
Adoption estimate89%45%
Models in this index79 / 7953 / 79

GGUF

The most versatile format. CPU, GPU, Apple Silicon — runs everywhere. Supports hybrid inference splitting weights across RAM and VRAM.

Strengths

  • Any hardware
  • CPU+GPU hybrid
  • Huge ecosystem
  • Beginner-friendly

Trade-offs

  • Slower than GPU-native
  • Not ideal for high concurrency

AWQ

Activation-Aware Weight Quantization. High-accuracy INT4 for NVIDIA. Pairs perfectly with vLLM for server deployment.

Strengths

  • Best accuracy at 4-bit
  • Blazing fast with vLLM
  • Excellent batch throughput

Trade-offs

  • NVIDIA only
  • More setup than GGUF

Models that ship both

These 53 models publish weights in both formats, so the two rows describe the same model rather than two different ones — the only place this comparison is measurable rather than editorial.

Models that ship both
ModelGGUF LevelQuality lossAWQ LevelQuality loss
Llama 3.1 405B InstructQ4_K_M2.3%AWQ INT43.5%
Qwen3 235B-A22B InstructQ4_K_M2.2%AWQ INT43.2%
Llama 4 Scout 17B (16E)Q4_K_M2.4%AWQ INT43.2%
Qwen2.5 72B InstructQ5_K_M1.1%AWQ INT43.5%
Llama 3.1 70B InstructQ5_K_M1.2%AWQ INT43.9%
Llama 3.3 70B InstructQ5_K_M1%AWQ INT43.7%
DeepSeek-R1-Distill-Llama-70BQ4_K_M2.4%AWQ INT43.5%
Mixtral 8x7B InstructQ4_K_M2.8%AWQ INT43.8%
Seed-OSS 36B InstructQ5_K_M1.3%AWQ INT43.8%
Yi 1.5 34B ChatQ4_K_M2.8%AWQ INT44%
Qwen3 32B InstructQ4_K_M2.5%AWQ INT43.6%
Qwen2.5-Coder 32B InstructQ4_K_M2.5%AWQ INT43.5%
Qwen3 30B-A3B InstructQ5_K_M1.1%AWQ INT43.4%
Qwen3-Coder 30B-A3B InstructQ5_K_M1%AWQ INT43.2%
Qwen3-VL 30B-A3B InstructQ8_00.3%AWQ INT43.7%
Gemma 3 27B ITQ4_K_M2.8%AWQ INT43.8%
Gemma 2 27B InstructQ5_K_M1.3%AWQ INT44%
Mistral Small 24B InstructQ4_K_M2.9%AWQ INT43.8%
Devstral Small 1.1 24BQ6_K0.6%AWQ INT44%
Magistral Small 1.2 24BQ6_K0.6%AWQ INT44%

Quality loss is perplexity increase against the unquantized weights — lower is better, and only comparable within one model.

Which to choose